Dr. Timothy Hubin
Submitted by gina on Tue, 2020-07-21 08:46
EPSCoR Research Focus:
Variable & Marginal Quality Water Supplies
Bernhardt Professor of Chemistry
Department of Chemistry and Physics
Southwestern Oklahoma State University
Spacer:
Please leave this field as it is.
Education:
B.S. | Chemistry | Kansas State University, Manhattan, KS | 1994
B.S. | Science Ed | Kansas State University, Manhattan, KS | 1994
Ph.D. | Chemistry | University of Kansas, Lawrence, KS | 1999
Research Interests:
Dr. Timothy J. Hubin, Bernhardt Professor of Chemistry at Southwestern Oklahoma State University, is a member of the OK NSF EPSCoR Track-1 RII Award titled Socially Sustainable Solutions for Water, Carbon, and Infrastructure Resilience in Oklahoma. The $20 million research project is a social science-led, multi-disciplinary collaboration among social, physical, biological, engineering, and computational scientists. More than thirty researchers from across the state are working together on the project, which began July 1, 2020.
Dr. Hubin's research supports the OK NSF EPSCoR project's Focus Area 3: Variable and Marginal Quality Water Supplies (V-MQW). The V-MQW Supplies focus area addresses issues surrounding Oklahoma’s water demands, which are projected to increase 600,000 acre-feet per year between 2007-2060. Reliable water supplies are needed to provide for these demands while meeting the state’s goal of capping freshwater use to 2010 levels. However, freshwater supplies are declining due to reservoir sedimentation and groundwater overdraft and are increasingly vulnerable to S2S variability. Concurrently, volumes of oil and gas ‘produced water,’ municipal wastewater, and stormwater are increasing with continued oil and gas development and urbanization. Disposal of produced waters has been correlated with seismicity, potentially impacting infrastructure and resulting in energy production curtailment in some regions. The challenge is finding a mix of solutions that allow Oklahoma’s diverse array of MQW to be economically treated for beneficial use to address water scarcity related to changing seasonal to sub-seasonal weather patterns, waste disposal, and infrastructure risk while supporting continued energy production and economic growth.
As a member of the V-MWQ Supplies focus area, Dr. Hubin will direct the synthesis and characterization of polymer-affixed transition metal catalysts having excellent stability and broad oxidizing ability under harsh aqueous conditions. Dr. Hubin has worked with this class of monomeric catalysts for decades and would like to make them useful for wastewater purification applications by affixing them to polymeric substrates, which will render them heterogeneous, recyclable solids. These solid catalyst polymers could potentially be reused for multiple cycles in a water purification system. The goal is to be able to transform by chemical oxidation those contaminants that may be biologically active (pharmaceuticals, pesticides, hormones, etc.) into inactive forms.
Dr. Hubin's research career has produced multiple patents. He currently holds seven U.S. and/or European patents in the fields of oxidation catalysts, consumer product bleach compositions, anti-viral transition metal complexes, and MRI contrast agents.
Key Publications:
- Shircliff, A. D; Burke, B. P.; Davilla, D. J.; Burgess, G. E.; Okorocha, F. A.; Shrestha, A.; Allbritton, E. M. A.; Nguyen, P. T.; Lamar, R. L.; Jones, D. G.; Gorbet, M.-J.; Allen, M. B.; Eze, J. I.; Fernandez, A. T; Ramirez, D.; Archibald, S. J.; Prior, T. J.; Krause, J. A.; Oliver, A. G.; Hubin, T. J. 2020. An Ethylene Cross-bridged Pentaazamacrocycle and its Cu2+ Complex: Constrained Ligand Topology and Excellent Kinetic Stability” Chem. Commun., 56, 7519-7522. https://doi.org/10.1039/d0cc00919a.
- Brewer, S. M.; Wilson, K. R.; Jones, D. G.; Reinheimer, E. W.; Archibald, S. J.; Prior, T. J.; Ayala, M. A.; Foster, A. L.; Hubin, T. J.; Green, K. N. 2018. Increase of Direct C-C Coupling Reaction Yield by Identifying Structural and Electronic Properties of High-spin Iron Tetra-azamacrocyclic Complexes. Inorg. Chem. 57:8890−8902. DOI: 10.1021/acs.inorgchem.8b00777.
- Maples, R. D.; Cain, A. N.; Burke, B. P.; Silversides, J. D.; Mewis, R.; D’huys, T.; Schols, D.; Linder, D. P.; Archibald, S. J.; Hubin, T. J. 2016. Aspartate-based CXCR4 Chemokine Receptor Binding of Cross-bridged Tetraazamacrocyclic Copper (II) and Zinc (II) complexes. Chem. Eur. J. 22:12916- 12930. DOI: 10.1002/chem.201601468.
- Jones, D. G.; Wilson, K. R.; Shircliff, A. D.; Zhang, Z.; Chen, Z.; Yin, G.; Prior, T. J.; Hubin, T. J. 2015. Synthesis, Structural Studies, and Oxidation Catalysis of the First Row Transition Metal Complexes of a 2-pyridylmethyl Pendant Armed Ethylene Cross-bridged Cyclam. Inorg. Chem. 54: 2221-2234. DOI: 10.1021/ic502699m.
- Matz, D. L.; Jones, D. G.; Roewe, K. D.; Gorbet, M.-J.; Zhang, Z.; Chen, Z.; Prior, T. J.; Archibald, S. J; Yin, G.; Hubin, T. J. 2015. Synthesis, Structural Studies, Kinetic Stability, and Oxidation Catalysis of the Late First Row Transition Metal Complexes of 4,10-dimethyl-1,4,7,10-Tetraazabicyclo[6.5.2] Pentadecane Dalton Trans. 44:12210-12224. DOI: 10.1039/c5dt00742a.
- Zhang, Z.; Coats, K. L.; Chen, Z.; Hubin, T. J.; Yin, G. 2014. Influences of Calcium (II) and Chloride on the Oxidative Reactivity of a Manganese (II) Complex of a Cross-bridged Cyclen Ligand. Inorg. Chem. 53:11937-11947. DOI: 10.1021/ic501342c.
- Archibald, S. J.; Lewis, E. A.; Hubin, T. J. 2011. Novel Antiviral Macrocycle Derivatives and Metal Complexes Incorporating Bridged Macrocycles. US Patent 8,034,800; granted October 11, 2011.
- Timmons, J. C.; Hubin, T. J. 2010. Preparations and Applications of Synthetic Linked Azamacrocycle Ligands and Complexes. Coord. Chem. Rev. 254:1661-1685. DOI: 10.1016/j.ccr.2009.09.018.
- Khan, A.; Nicholson, G.; Greenman, J.; Madden, L.; McRobbie, G.; Pannecouque, C.; De Clercq, E.; Silversides, J. D.; Ullom, R.; Maples, D. L.; Maples, R. D.; Hubin, T. J.; Archibald, S. J. 2009. Binding Optimization through Coordination Chemistry: CXCR4 Chemokine Receptor Antagonists form Ultrarigid Metal Complexes” J. Am. Chem. Soc. 131:3416-3417. DOI: 10.1021/ja807921k.
- Hubin, T. J.; McCormick, J. M.; Collinson, S. R.; Perkins, C. M.; Alcock, N. W.; Kahol, P. K.; Raghunathan, A.; Busch, D. H. 2000. New Iron (II) and Manganese (II) Complexes of Two Ultra-rigid, Cross-bridged Tetraazamacrocycles for Catalysis and Biomimicry. J. Am. Chem. Soc. 122:2512. DOI: 10.1021/ja990366f.
- Busch, D. H; Collinson, S. R.; Hubin, T. J. 2005. Catalysts and Methods for Catalytic Oxidation. US Patent 6,906,189 B2; granted June 14, 2005.
Curriculum Vitae:
